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La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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robert - Philips Norelco Electric Shaver, they just keep getting better !

Can't get a better shaver, this is only my third Philips Norelco Electric Shaver in almost 50 years and they just keep getting better. Price is excellent and the charge last a long time, I like the feature that you can rinse it off in water after each use without breaking it.

Mikkel - They're check regesters...

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