La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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  • Lori A. Grove-flynn - Defective and Very Hard to Get Help

    My husband purchased this for my birthday (at my request). It arrived quickly but when it was assembled it did not run. The incline did not work, the motor would not accelerate and it was very loud. We have called customer service numerous times but it took 2 weeks to get a repair man to come to our house even though the unit was defective from the first. Once the repair man came he determined a bar on the bottom of the treadmill was bent and cracked and unable to be repaired. We now have an unfixable treadmill sitting in our master bedroom waiting to be returned.

  • George P. Burdell - Marginal contribution to the game

    It's OK. It keeps the game fresh. But it's only 20 cards and it's just ok. Adds an interesting new mechanic but doesn't really improve the fun of the base game by a lot. Not really worth the 12.99 when you consider the base game is $20