La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.
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I read constantly and most enjoy books that have people in them that I either like/love or hate. People that seem alive to me. This book has that quality, plus the fact that I became involved in it to the point that I didn't want to put it down. I finished it in one day because it was just that interesting! And went on to get Book No. 2 and finished that one the next day.
For readers of literary journals out there, most of the published stories will not surprise you: Ron Rash, Wells Tower, etc. are featured in here. Although the selected stories are predictable, that does not take away their right to be published in this collection as they are indeed the best of the year. All in all, it is an excellent edition and worth purchasing.
PLEASE READ: This is sold for $20.00 cheaper directly from the manufacturer's website. If you don't mind waiting a little longer for shipping, you'll save a lot of money. I'm not affiliated with this company by any means, I'm just trying to save you all some cash!