La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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  • Babs - Take a trip into a dog's sense of smell

    Highly engaging voyage into the nostrils of a dog. What?! Yes, that's right. Ms. Horowitz takes us through the experience of a dog's sense of smell and the amazing journey those smell particles take to educate the dog on their surroundings, be it danger or favorite food. In a science-based, but reader friendly format, we learn about the intricacies of smell in the dog's world and how differently they use this sense from their humans. The book puts forth the scientific studies being done in this area and their connection with aeronautics and other seemingly unconnected areas of research. Very enjoyable and educational! I will never look at my dog's nose the same way again.

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    Virgil is the likeable character as usual. John Sanford has him so down his every move and thought seems right. Good read as are all his books.

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    Do a bit of research & you'll find ACTIVE Manuka honey has many, many uses. I've used the honey for many of them....digestive issues (for my canine companion as well), skin issues, wounds, infections, the list goes on. I always have a jar on hand as part of my own home-grown 1-aid kit. Because of its consistently high ratings -- across vendor sites --I would say you can't go wrong with Wedderspoon as a brand.