La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

www.aslm.org Review:

ASLM African Society for Laboratory Medicine, ASLM - ASLM: African Society for Laboratory Medicine -- a pan-African organisation strengthening medical laboratory networks and systems in Africa.

http://www.aslm.org/stay-informed/press-room/lab-culture-newsletter/ ASLM Lab Culture Newsletter: ASLM - Lab Culture is the premier quarterly newsletter of ASLM, covering laboratory best practices and global health security.

http://www.aslm.org/who-we-are/team/ ASLM Team Members - Click to read more about the African Society for Laboratory Medicine (ASLM) team members.

http://www.aslm.org/what-we-do/global-health-security/ ASLM Global Health Security in Africa - ASLM recognises that emerging global health security threats now require even more responsive, harmonised, and integrated alignment of laboratory networks.

http://www.aslm.org/what-we-do/slipta/ ASLM SLIPTA Programme - Through standardised processes, the SLIPTA programme measures and evaluates the progress of laboratory systems towards international accreditation.

http://www.aslm.org/what-we-do/aphln/ ASLM African Public Health Laboratory Network (APHLN) - The ASLM-led APHLN is a network of national public health labs promoting regional collaboration and coordination to address African healthcare priorities.

http://www.aslm.org/resource-centre/ebola-resources-for-the-laboratory/ ASLM Ebola Resources for the Laboratory - ASLM has compiled laboratory-specific Ebola resources for laboratorians, clinicians, policy makers and more.

http://www.aslm.org/resource-centre/hiv-viral-load-testing/ ASLM HIV Viral Load Testing - ASLM - Accurate monitoring of HIV in a patient is essential for assessing the effectiveness of antiretroviral therapy (ART) and preventing unnecessary switches to costly second-line drug therapy. Unfortunately, viral load testing is not widely available due to limited laboratory capacity and cost considerations, and many countries are exploring ways to expand access to this test.

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UPDATE 12/2/2011: I took this for while and then stopped. Problems returned worse than ever. Started taking them again and problems were not going away. Went to the doctor, who told me not to take these because they can often make the symptoms worse, especially if you don't keep taking them FOREVER. Just be aware that this is not a cure all.

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