La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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  • Jordan Wittenhagen - 2015 crosstrek

    It fit my crosstrek when I removed the top rubber cushions, it fits snug but I'm afraid it might scratch a little missing the cushions but not worried enough to spend the extra $70 to get the Subaru crossbars

  • PJDour - NRS Pilot Knofe

    Recently bought the NRS pilot knife for a week long kayak camping trip. I like the secure attachment to my PFD, but the nicest feature was the quick and sure release. It's somewhat "spring loaded" using the clips that secure it to the sheath. The blunt/flat point ensures no accidental punctures, and the formed semi-circle cutter makes fast cutting of ropes a snap. The quick release mechanism also locks the knife back in with a snap - if it does not snap, it's not in. Again, something almost foolproof, which is nice if you are reacting to an issue on the water. Great overall blade. I also ordered the Gerber Rivermate at the same time, as I have beena Gerber fan fr 40+ years, but the NRS Pilot wins my vote as the knife to carry on the water.

  • Dr. P - Definitely NOT 100% Frankincense

    This states it is 100% oil and no carrier oil added but it is not. After I opened it and started using it, it even changed smelling from slightly frankincense to alcohol :( Don't waste your money on this one!

  • Alan D. Pelzsharpe - Avoid the Cloud version of this product like the plague

    SmartDraw today has a Cloud version that many if not most people would presumably chose over the desktop version. However, the Cloud version lacks a lot of core functionality. For example it has no Project Management tools (Gantt charts) etc. The reason for the one star is that you would never know that from the advertising or website - no feature comparison of the two versions etc. Once you buy the Cloud version (around $150) and find out its useless for your purposes they invite you to spend more to get the missing features.