La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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  • M. Collins - Great bag!

    I hate taking roller bags on airplanes. They are bulky and allow me a little bit more stuff than I'd like to take on a short/weekend trip. So this is a great solution! I alternate between carrying it as a backpack and as a shoulder bag, but either way, its easy to carry. But at the same time, it has a lot more space than I would have expected! I was able to carry enough for a 5 day trip, plus extra shoes and toiletries.

  • Amazon Customer - Often helpful, often flawed.

    Although being notorious for it's insight, I found Shrunk' s guide rather arbitrary at times. For example, towards the end of the brief informative, Strunk states that "Alright" should always be written as two words (all right). Not only this, but he also fails to provide exceptions to broad rules. Billy S. says (rule eleven, I think) that all paragraphs should include a topic sentence and a conclusive sentence (very wise third grade insight). While generally helpful, he fails to address the obvious exceptions: paragraph changes dues to dialogue.

  • InspectorGadget - Bad company, bad product

    I had Web root a few years ago, admittedly. But that year I got hit by a succession of THREE really nasty rootkit viruses in drive-by attacks from celebrity web sites. I was on the phone to them constantly over the period of a few months and they were utterly uninterested in how and why their product failed so miserably. It was obviously poorly designed and written because it would get modal and bogged down when attacked and a rapid succession of attacks would wholly overwhelm it.