La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

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Country: 184.173.128.237, North America, US

City: -77.4512 Virginia, United States

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    What a contrast MS and Apple are. Apple seems it can do no wrong - everything it does seems carefully calculated and well planned. The Customer Experience always of paramount importance. Then there is MS who seem to look for ways to screw themselves. Granted Windows 7 was a big improvement, however overall expectations after years of disappointment we're truthfully not that high - just getting an Windows OS that worked fairly reliable had focus happy. But then to follow a little success with the decision to NOT offer upgrade pricing on Office 2010 was as bone-headed as decisions come. I am sick of MS price gouging mentality.

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    Flow was great, bridges was a bit harder but still fun and noe hexes! Same games with a little twist! Still fun!