La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.
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I've seen a lot of poor reviews on this product and while it's taken me a while to figure out where everything is, it still works. The UI is a bit confusing. I wouldn't say that things are easily found or in a common sense location... but "help" points you in the right direction. The UI learning curve is a bit steeper than older versions of the program, but it still gets the job done once you figure it out. And, it doesn't crash as much as my 2006 version with Win7, so that's huge plus. Backups are handy and nice to have.
After using this book, I would highly recommend it to students that are getting gear up to take the NCLEX. The content is simple & easy to understand. It would have been perfect (5 Stars) if only there was a CD that came with it, but it's pretty inexpensive so it's really worth purchasing. Best of Luck to the candidates out there.