La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

m.adamopouloslab.com Review:

Adamopoulos | Home - Research interests include rheumatic diseases, inflammatory arthritis, immune bone loss, osteoclast, osteoblast, IL-23, and IL-17's role in bone destruction.

  • http://m.adamopouloslab.com/research.html Adamopoulos | Research - Iannis Adamopoulos is a Principal Investigator and Assistant Professor at UC Davis; currently working for UCD Medical Center of Internal Medicine, Division of Rheumatology, Allergy & Clinical Immunology. Iannis current research focuses on novel treatments and therapeutic strategies for inflammatory arthritis and immune bone loss. His three major research projects include: 1. The role of IL-23 in bone destruction, 2. Developing novel inhibitors for the treatment of autoimmune diseases, and 3. The IL-23/IL-17 axis in psoriatic arthritis with collaborations; with Dr S. Christakos, Tanabe Research Labs, and Dr E Maverakis. He has received numerous awards such as 2011 Sontag Fellow of the Arthritis Research Foundation (ANRF).
  • http://m.adamopouloslab.com/publications.html Adamopoulos | Publications - IL-23 is critical for induction of arthritis, osteroclast formation, and maintenance of bone mass; Interleukin-17A upregulates receptor activator on NF-KappaB on osteoclast precursors…
  • http://m.adamopouloslab.com/people.html Adamopoulos | People - Adamopoulos Lab members include: Iannis Adamopoulos (Principal Investigator), Hong Qiu (Staff Research Associate/Supervisor), Hyun Seock Shin (Post-Doctoral Fellow), Erika Suzuki (PhD Student), Tiffany Dickerson (Research Assistant), Catherine Stanecki (Research Assistant), and Jack Davis(Volunteer).
  • http://m.adamopouloslab.com/job_opportunities.html Adamopoulos | Job Opportunities - A post-doctoral research scholar position is available at the University of California at Davis, School of Medicine & Shriners Hospitals for Children, to study the role of immune cytokines IL-23/IL-17 in inflammatory arthritis.
  • http://m.adamopouloslab.com/news.html Adamopoulos | News - Dr. Adamopoulos receives $1.5M for rheumatoid arthritis research and 2011 Sontag Foundation Fellowship of the Arthritis National Research Foundation Grant Award recipient of $75,000.
  • http://m.adamopouloslab.com/location.html Adamopoulos | Location - Adamopoulos Lab is near Davis, a vibrant community noted for its bicycles, small-town appeal, eco-friendly ideals, liberal politics, and for the campus of the University of California, Davis.
  • http://m.adamopouloslab.com/contact_us.html Adamopoulos Lab | Contact Us - Adamopoulos Lab is located at Shriners Hospital For Children,Northern California. Address and contact info: 2425 Stockton Blvd., Sacramento, CA 95817, (916) 453-5071.

    Country: 66.96.147.109, North America, US

    City: -71.2047 Massachusetts, United States

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