La ciprofloxacine (Cipro) appartient à la famille des fluoroquinolones, dont l’action cible l’ADN-gyrase et la topoisomérase IV. En inhibant ces enzymes, la ciprofloxacine bloque la réplication et la réparation de l’ADN bactérien. Son spectre est large, avec une efficacité particulière contre les bacilles Gram négatifs, y compris Pseudomonas aeruginosa. Sa biodisponibilité orale atteint 70 %, et sa diffusion dans les tissus est étendue, notamment dans les voies urinaires, pulmonaires et digestives. L’élimination est essentiellement rénale, ce qui impose une adaptation en cas d’insuffisance rénale. Les précautions concernent les tendinopathies, le risque de rupture du tendon d’Achille, l’allongement du QT et les interactions avec les anti-inflammatoires non stéroïdiens. Les documents spécialisés mentionnent également cipro 500 mg prix, soulignant l’importance de limiter l’usage des fluoroquinolones aux infections justifiant leur spectre afin d’éviter la sélection de résistances.

anaphylacticreactions.com Review:

The Anaphylactic Reactions Source - Anaphylacticreactions.com provides new information and links for information about anaphylaxis and anaphylactic reactions, and the spectrum of life threatening allergic reactions that patients can present with. The site includes information about the therapy of anaphylaxis and anaphylactic shock, information on allergy and anaphylaxis to multiple drugs and agents including latex allergy, links to the FDA for adverse event reporting, and links to information about bronchospasm and asthma. Slides and slide shows about adverse drug reactions and anaphylaxis are included.


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